Case no. 1 /back/
|
Diagnosis: Papillary carcinoma
|

|
epithelial cells in monolayered sheets, papillary formation
the cells have well-defined, uniformly dense cytoplasm
central, slightly irregular, enlarged nucleus with fine chromatin pattern and nuclear indentation- grooves
|
| Case no. 2 /back/ |
Diagnosis: Hurthle cell neoplasm |

|
loose
aggregate of large, polygonal to oval cells with abundant, granular
cytoplasm and large nuclei with uniformly distributed chromatin
d.d. malignancy-Hurthle cell carcinoma
|
| Case no. 3 /back/ |
Diagnosis: Pleomorphic adenoma |

|
purple staining chondromyxoid background
epithelial cells, relatively uniform in size and shape, single or in clusters
cells with poorly defined cytoplasm and round, hyperchromatic nuclei
d.d. adenoid cystic carcinoma (submandibular or minor glands, myxoid background in adenoma pleomorphe)
mucoepidermoid carcinoma (abundant cytoplasm, slight increase cytoplasmic keratin, bizzare nuclei)
|
| Case no. 4 /back/ |
Diagnosis: Parathyroid adenoma |

|
loosly attached cell groups, ill-defined cytoplasmatic membrane, round nuclei, common naked nuclei
d.d. hyperplasia, thyroid tissue
|
| Case no. 5 /back/ |
Diagnosis: Infiltrating ductal carcinoma |

|
atypical cells in the clusters
hyperchromatic, vesicular, round nuclei with variation in size and shape
chromatin is unequally distributed, nuclear membranes are irregular but well defined
d.d. carcinoma in situ
|
| Case no. 6 /back/ |
Diagnosis: Schwannoma |

|
twisted structures of closely packed spindle, stellate or bipolar cells in fibrillar background
sometimes iregular nucleus and marked degree of cytological pleomorphism
d.d. MPNST- solid areas, no twisted structures, monotonous cell population, hypercellularity
|
| Case no. 7 /back/ |
Diagnosis: Glioblastoma |

|
ill-defined margin appearance of the pleomorphic cell with large nuclei
large cells with abudant cytoplasm, marked variation in size and shape, binucleation and bizzare nuclei
d.d. poorly differentiated neoplasm (metastatic carcinoma
|
| Case no. 8 /back/ |
Diagnosis: Pituitary gland adenoma |

|
cells smeared less evently producing a clumped effect, single cell population
abundant cytoplasm, uniform cell population, oval to rounded nucleus with fine chromatin distribution
d.d. normal pituitary gland-cytological heterogeneity
|