12th Ljudevit Jurak
International Symposium on
June 1-2, 2001
|GIANT CYST OF THE CHOROID PLEXUS IN AN ELDERLY
MAN - A CASE REPORT
B. Božiæ*, A. Kogler*, J. Hat**, T. Sajko*
”Ljudevit Jurak” University Department
of Pathology , *Department of Neurosurgery,
**Department of Diagnostic and Interventional Radiology
”Sestre milosrdnice” University Hospital, Zagreb, Croatia
|Aim of this case report is to present a rare symptomatic choroid plexus
cyst in an 70 year-old man.
Small asymptomatic cysts of the choroid plexus are a frequent incidental
finding at necropsy. Their size usualy does not extend beyond 1,5-2 cm
in diameter. Only rarely may they be large enough to cause symptoms.
The patient and methods - A 70 year old man was admitted to hospital
due to headaches which lasted about two months. Magnetic resonance imaging
(MRI) showed a large lesion 70,2 x 47,4 x 56,7 mm in the left
temporoparietal region with compression of the lateral ventricle. Patient
uderwent surgery. Pathohistological analysis of the intraoperative
and postoperative samples determined parts of the choroid plexus cyst.
Immunohystochemistry was performed using primary antibodies purchased at
the DAKO Corporation. PAP method was used. The epithelium of the
choroidal cyst showed strong immunoreactivity for cytokeratin, S-100 protein,
vimentin and NSE.
Total removal of the cyst has been performed, and the patient achieved
Conclusion and actualities Huge and symptomatic cysts of
the choroid plexus are rare. Before 1985 ten such symptomatic cases had
been reviewed from the literature. In the recent literature we came across
four cases of symptomatic choroidal cysts in adults.
Today, prenatal sonographic studies in the second and third trimesters
are numerous and determine the presence of choroid plexus cysts in the
fetus with an incidence of about 0,65%. Associated anatomic anomalies include
a chromosomal abnormality (trisomies 18 and 21 are possibl). It is
debatable weather choroid plexus cyst in a fetus is a benign anatomic variant
or pathologic entity.
Darmoul M et al. Neurochirurgie 1999 Mar;45(1): 45-8
Maruiwa H et al. No Shinkei Geka 1966 Dec; 24 (12): 1113-7
Yoder PR et al. Obstet Gynecol 1999May;93 (5Pt2):869-72
Coca S et al. Histol Histopathol 1993 Oct; 8(4):651-4