12th Ljudevit Jurak International Symposium on
Comparative Pathology
Zagreb
June 1-2, 2001
 

POSTER PRESENTATION
MORPHOLOGICAL CHARACTERISTICS AND SURVIVAL AFTER SURGICAL THERAPY OF COLORECTAL CANCER IN REGION OF NAŠICE
V. Èaèinoviæ, D. Lenz, V. Ilakovac
General Hospital, Našice, Croatia
Colorectal carcinoma has a wide distribution in Croatia, with the highest incidence rate in Istria, Slavonia and region of Dubrovnik. (1) Colorectal cancer is the second most common fatal malignancy in both sexes combined, after lung cancer. Colorectal cancer is largely an environmental disease, but genetic susceptibility has an important role. Two highly penetrating autosomal dominant predisposition syndromes: hereditary non-polyposis colorectal cancer and familial adenomatous polyposis together account for 2-10% of all cases of colorectal cancer.
The overall five-year survival rate is around 40%, but survival can be as high as 70% after curative surgery. The morbidity associated with the disease and its treatment is considerable. Almost all patients require surgical resection. Unfortunately, palliation is the only realistic hope for the substantial proportion of patients who already have disseminated disease. (2,3) One hundred and four cases of colorectal carcinoma were analyzed after surgical and oncological treatment in interval years (1986.-1999.) All patients were mostly of the rural regions. The data about patients includes sex, age, date of operation and date of death. The data regarding colorectal tumors includes size, localizations, involvement of the circumference wall bowel, histological type of the tumors, number of metastatic involvement of lymphatic nodules, histological differentiations tumor tissues, pathological staging, and prevalence of adenomas. Survival probabilities were estimated by the univariante Kaplan-Meier method.
Multivariate analyses were performed by the Cox regression model.
This paper describes morphological characteristics of colorectal tumors and survival after surgical and oncological treatment.

References:

  1. Turiæ M, Kolariæ K, Eljuga D. Klinièka onkologija. 1. izd. Zagreb: Nakladni zavod Globus, 1996:557-627.
  2. Boyle P, Zardze DG., Smans M. Descriptive epydemiology of colorectal cancer. Int J Canc 1985;36(1):9-18.
  3. Adami HO. Aspects of descriptive epidemiology and survival in colorectal cancer. Scand J Gastroenterol 1988;149:6-20.
Poster Presentation