12th Ljudevit Jurak
International Symposium on
June 1-2, 2001
|CLINICOPATHOLOGICAL FEATURES OF PRIMARY INTESTINAL
LYMPHOMA IN TAIWAN: A STUDY OF 28 RESECTED CASES
|Shih-Sung Chuang, Ching-Nan Lin
Department of Pathology, Chi-Mei Medical Center, Tainan, Taiwan
|Aim: We conducted this retrospective study for a better understanding
of primary intestinal lymphoma (PIL) in Taiwan.
Methods: We studied 28 surgically resected cases with a review
of history and H&E sections and paraffin immunohistochemistry.
Results: There were 16 males and 12 females. The median age
was 66. The major presenting symptom was abdominal pain (n = 19, 67.9%).
10 patients (35.7%) were complicated with perforation at presentation.
Two patients had multicentric tumors. The most common location of lymphoma
involvement was the ileum (n = 14, 50.0%). 26 cases (92.9%) were of B-cell
lineage and 2 (7.1%) T-cell. They were classified according to REAL as
diffused large B-cell lymphoma (n = 20, 71.4%), extranodal marginal zone
B-cell lymphoma (n = 3, 10.7%), Burkitt’s lymphoma (n = 2), follicular
lymphoma (n = 1), and intestinal T-cell lymphoma (n = 2). Seven died of
complications within 2 months after operation and 2 were lost to follow-up.
Of the remaining 19 patients, there were 5 deaths within one year. The
1- and 2-yr survival rate was 66.7% and 41.6%, respectively.
Conclusion: In this study, we have characterized the clinicopathological
findings of one case each of appendiceal MZL and ileal CD30+ enteropathy-associated
T-cell lymphoma. We found that PIL in Taiwan occurs in old age group with
a slight male predominance and a relatively aggressive clinical course.
We confirmed that the PIL in Taiwan shows the pattern of the